ORC1L monoclonal antibody, clone 7F6/1
产品名称： ORC1L monoclonal antibody, clone 7F6/1
英文名称： ORC1L monoclonal antibody, clone 7F6/1
产品编号： MAB7324
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against ORC1L.
- Immunogen:
- Full length human ORC1L.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- ORC1 (7F6/1). This antibody detects a band of 120 KDa.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS
- Storage Instruction:
- Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:1250-1:2500)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1.
Burke TW, Cook JG, Asano M, Nevins JR.J Biol Chem. 2001 May 4;276(18):15397-408. Epub 2001 Jan 24.
- Application Image
- Western Blot
- Entrez GeneID:
- 4998
- Gene Name:
- ORC1L
- Gene Alias:
- HSORC1,ORC1,PARC1
- Gene Description:
- origin recognition complex, subunit 1-like (yeast)
- Omim ID:
- 601902
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. [provided by RefSeq
- Other Designations:
- OTTHUMP00000009797,OTTHUMP00000009798,origin recognition complex 1,origin recognition complex, subunit 1,origin recognition complex, subunit 1, S. cerevisiae, homolog-like,replication control protein 1
- Gene Pathway